Hexokinase II (HK2) Rabbit Polyclonal Antibody
CAT#: TA326886S
Rabbit anti-HK2 Polyclonal Antibody
Size: 100 ul
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CN¥ 800.00
货期*
2周
规格
Product images
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Specifications
Product Data | |
Applications | ICC/IF, IHC, WB |
Recommend Dilution | WB 1:500 - 1:2000;IF 1:50- 1:200 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant protein of human HK2 |
Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | hexokinase 2 |
Database Link | |
Background | Hexokinase catalyzes the conversion of glucose to glucose-6-phosphate, the first step in glycolysis. Four distinct mammalian hexokinase isoforms, designated as hexokinase I, II, III, and IV (glucokinase), have been identified. Hexokinases I, II, and III are associated with the outer mitochondrial membrane and are critical for maintaining an elevated rate of aerobic glycolysis in cancer cells (Warburg Effect)in order to compensate for the increased energy demands associated with rapid cell growth and proliferation. |
Synonyms | HKII; HXK2 |
Reference Data | |
Protein Families | Druggable Genome |
Protein Pathways | Amino sugar and nucleotide sugar metabolism, Fructose and mannose metabolism, Galactose metabolism, Glycolysis / Gluconeogenesis, Insulin signaling pathway, Metabolic pathways, Starch and sucrose metabolism, Type II diabetes mellitus |
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