Cyclophilin A (PPIA) Rabbit Polyclonal Antibody

CAT#: TA326885

PPIA Rabbit Polyclonal Antibody



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热销推荐

CNY 1,999.00

CNY 2,700.00


货期*
2周

规格
    • 100 ul

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经常一起买 (4)
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Recombinant protein of human peptidylprolyl isomerase A (cyclophilin A) (PPIA), 20 µg
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Recombinant protein of human peptidylprolyl isomerase A (cyclophilin A) (PPIA), 100 µg
    • 100 ug

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Specifications

Product Data
Applications WB
Recommend Dilution WB 1:500 - 1:2000
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human PPIA
Formulation PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name peptidylprolyl isomerase A
Background Cyclophilins are a highly conserved family of peptidylprolylcis-trans-isomerases (PPIA) that are targets of the immunosuppressant drug cyclosporin A (CsA). The complex of cyclophilin and CsA can bind to and inhibit calcineurin which leads to inhibition of the transcription factor NFAT and decreased production of cytokines. As isomerases, cyclophilins have been proposed to aid in protein folding. Cyclophilin A can bind to the p55 Gag protein of HIV and appears necessary for HIV infection There is also some evidence that cyclophilins have nuclease activity and play a role in apoptosis.
Synonyms CYPA; CYPH; HEL-S-69p
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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