PPAR gamma (PPARG) Rabbit Polyclonal Antibody
CAT#: TA326810
PPARG Rabbit Polyclonal Antibody
Size: 30 ug
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Specifications
Product Data | |
Applications | ICC/IF, IHC |
Recommend Dilution | IF 1:50 - 1:100 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | N term -peptide of human PPARG |
Formulation | Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3 |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | peroxisome proliferator activated receptor gamma |
Database Link | |
Background | Peroxisome proliferator-activated receptor ? (PPAR?) is a member of the ligand-activated nuclear receptor superfamily and functions as a transcriptional activator (1). PPAR? is preferentially expressed in adipocytes as well as in vascular smooth muscle cells and macrophage (2). Besides its role in mediating adipogenesis and lipid metabolism (2), PPAR? also modulates insulin sensitivity, cell proliferation and inflammation (3). PPAR? transcriptional activity is inhibited by MAP kinase phosphorylation of PPAR? at Ser84 (4,5).1. Tontonoz, P. et al. (1995) Curr. Opin. Genet. Dev. 5, 571-576.2. Rosen, E.D. et al. (1999) Mol. Cell 4, 611-617.3. Murphy, G.J. and Holder, J.C. (2000) Trends Pharmacol. Sci. 21, 469-474.4. Camp, H.S. and Tafuri, S.R. (1997) J. Biol. Chem. 272, 10811-10816.5. Adams, M. et al. (1997) J. Biol. Chem. 272, 5128-5132. |
Synonyms | CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma |
Reference Data | |
Protein Families | Druggable Genome, Nuclear Hormone Receptor, Transcription Factors |
Protein Pathways | Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer |
Documents
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