PPAR gamma (PPARG) Rabbit Polyclonal Antibody

CAT#: TA326810

PPARG Rabbit Polyclonal Antibody

Size: 30 ug 100 ul



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CNY 1,999.00

CNY 2,700.00


货期*
2周

规格
    • 100 ul

Product images

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Specifications

Product Data
Applications ICC/IF, IHC
Recommend Dilution IF 1:50 - 1:100
Reactivity Human, Mouse, Rat
Host Rabbit
Clonality Polyclonal
Immunogen N term -peptide of human PPARG
Formulation Store at -20C or -80C. Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name peroxisome proliferator activated receptor gamma
Background Peroxisome proliferator-activated receptor ? (PPAR?) is a member of the ligand-activated nuclear receptor superfamily and functions as a transcriptional activator (1). PPAR? is preferentially expressed in adipocytes as well as in vascular smooth muscle cells and macrophage (2). Besides its role in mediating adipogenesis and lipid metabolism (2), PPAR? also modulates insulin sensitivity, cell proliferation and inflammation (3). PPAR? transcriptional activity is inhibited by MAP kinase phosphorylation of PPAR? at Ser84 (4,5).1. Tontonoz, P. et al. (1995) Curr. Opin. Genet. Dev. 5, 571-576.2. Rosen, E.D. et al. (1999) Mol. Cell 4, 611-617.3. Murphy, G.J. and Holder, J.C. (2000) Trends Pharmacol. Sci. 21, 469-474.4. Camp, H.S. and Tafuri, S.R. (1997) J. Biol. Chem. 272, 10811-10816.5. Adams, M. et al. (1997) J. Biol. Chem. 272, 5128-5132.
Synonyms CIMT1; GLM1; NR1C3; PPARG1; PPARG2; PPARgamma
Reference Data
Protein Families Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Protein Pathways Huntington's disease, Pathways in cancer, PPAR signaling pathway, Thyroid cancer
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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