SDF1 (CXCL12) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, ICC: 5 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	CXCL12 antibody was raised against a 16 amino acid peptide near the center of human CXCL12
Formulation	CXCL12 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	CXCL12 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 15 kDa; Observed: 18 kDa
Gene Name	C-X-C motif chemokine ligand 12
Database Link	NP_001171605 Entrez Gene 6387 Human UniProt ID P48061
Background	The CXCL12 protein, also known as SDF1, is a stromal cell-derived alpha chemokine member of the intercrine family. CXCL12 functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4 (CXCR4) and CXCR7, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis (reviewed in 1). Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections (2).
Synonyms	IRH; PBSF; SCYB12; SDF1; TLSF; TPAR1
Reference Data

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