CERD4 (DPF3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL, IHC: 5 ug/mL, IF: 20 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	DPF3 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human DPF3
Formulation	DPF3 antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	DPF3 antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 39 kDa; Observed: 50 kDa
Gene Name	double PHD fingers 3
Database Link	NP_036206 Entrez Gene 70127 MouseEntrez Gene 8110 Human UniProt ID Q92784
Background	The DPF3 protein, also known as Cerd4, is a member of the d4 gene family of transcription modulators that also includes DPF1/Neud4 and DPF2/Requiem (1). DPF3 has been shown to be a epigenetic key factor for heart and muscle development and can bind to methylated and acetylated lysine residues of histone 3 and 4, suggesting that DPF3 may play a role in recruiting chromatin remodeling complexes to acetylated histones (2). Two isoforms of DPF3, DPF3a and DPF3b, are required as transcriptional co-activators in SWI/SNF complex-dependent activation of the NF-kappaB RelA/p50 heterodimer (3).
Synonyms	BAF45C; CERD4
Reference Data
Protein Families	Transcription Factors

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