CD160 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	CD160 antibody was raised against a 17 amino acid peptide near the center of human CD160.
Formulation	CD160 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	CD160 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 20 kDa; Observed: 25 kDa
Gene Name	CD160 molecule
Database Link	NP_008984 Entrez Gene 54215 MouseEntrez Gene 11126 Human UniProt ID O95971
Background	CD160, also known as BY55, is a lipid-anchored cell membrane glycoprotein that contains one immunoglobulin-like domain (1). It is expressed in small intestine, spleen and functional NK and T cytotoxic lymphocytes (1,2). CD160 exists as a disulfide-linked homomultimer that functions as a receptor for MHC (major histocompatability complex) molecules and is thought to regulate the function of NK cells (2,3). Additionally, CD160 interacts with TNFRSF14 and, via this interaction, is able to negatively regulate CD4+ T cell activation, indicating a role in immune system regulation (4).
Synonyms	BY55; NK1; NK28
Reference Data
Protein Families	Druggable Genome

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