CEACAM5 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	CEACAM5 antibody was raised against a 15 amino acid peptide near the center of human CEACAM5
Formulation	CEACAM5 Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	CEACAM5 Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 77 kDa; Observed: 80 kDa
Gene Name	carcinoembryonic antigen related cell adhesion molecule 5
Database Link	NP_004354 Entrez Gene 73250 MouseEntrez Gene 1048 Human UniProt ID P06731
Background	CEACAM5 is a member of the carcinoembryonic antigen (CEA) family, which belongs to the immunoglobulin superfamily (1,2). CEACAM proteins are involved in cell-cell recognition and modulate cellular processes that range from the shaping of tissue architecture and neovascularization to the regulation of insulin homeostasis and T-cell proliferation (2). CEACAM5 has been shown to be overexpressed in a majority of carcinomas and has been suggested to be a intercellular adhesion molecule involved in cancer invasion and metastasis (3).
Synonyms	CD66e; CEA
Reference Data

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