TFPI Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 1 - 2 ug/mL
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	TFPI antibody was raised against a 13 amino acid peptide near the amino terminus of human TFPI.
Formulation	TFPI Antibody is supplied in PBS containing 0.02% sodium azide.
Concentration	1 mg/ml
Purification	TFPI Antibody is affinity chromatography purified via peptide column.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	Predicted: 33 kDa; Observed: 30 kDa
Gene Name	tissue factor pathway inhibitor
Database Link	NP_006278 Entrez Gene 21788 MouseEntrez Gene 29436 RatEntrez Gene 7035 Human UniProt ID P10646
Background	TFPI Antibody: Tissue factor pathway inhibitor (TFPI), also known as lipoprotein-associated coagulation inhibitor, is a protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation (1). TFPI is glycosylated and predominantly found in the vascular endothelium and plasma in both free forms and complexed with plasma lipoproteins. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. TFPI inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop (1).
Synonyms	EPI; LACI; TFI; TFPI1
Reference Data
Protein Families	Secreted Protein
Protein Pathways	Complement and coagulation cascades

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