mfsd2aa Rabbit Polyclonal Antibody
CNY 5,808.00
CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
Product Data | |
Applications | IF, IHC, WB |
Recommend Dilution | WB: 1 - 2 ug/mL, ICC: 5 ug/mL, IF: 20 ug/mL |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | MFSD2A antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human MFSD2A. The immunogen is located within the last 50 amino acids of MFSD2A. |
Formulation | MFSD2A Antibody is supplied in PBS containing 0.02% sodium azide. |
Concentration | 1 mg/ml |
Purification | MFSD2A Antibody is affinity chromatography purified via peptide column. |
Conjugation | Unconjugated |
Storage Condition | Antibody can be stored at 4°C up to one year. Antibodies should not be exposed to prolonged high temperatures. |
Gene Name | major facilitator superfamily domain containing 2aa |
Database Link | |
Background | MFSD2A Antibody: Multidrug transporters, such as MFSD2A, are membrane proteins that expel a wide spectrum of cytotoxic compounds from the cell and render cells resistant to multiple drugs. Major Facilitator Superfamily (MFS) members are capable of transporting various substrates such as sugars, polyols, drugs, neurotransmitters, amino acids, peptides, and inorganic anions, although most members are substrate-specific. MFSD2A is a novel lung cancer tumor suppressor gene that regulates cell cycle progression and matrix attachment and has recently been described as the human receptor for syncytin-2, a retrovirus-derived protein mediating fusion of placental trophoblasts. MFSD2A is expressed in many tissues and is highly induced in liver and brown adipose tissue (BAT) during fasting. The activation of the betaAR signaling pathway plays a major role in the induction of MFSD2A expression during adaptive thermogenesis. |
Synonyms | MCPH15; MFSD2; NLS1 |
Reference Data |
Documents
Product Manuals |
FAQs |
SDS |
Resources
抗体相关资料 |