Cacng2 Mouse Monoclonal Antibody [Clone ID: S245-36]

Specifications

Product Data
Clone Name	S245-36
Applications	WB
Recommend Dilution	WB: 1ug/ml
Reactivity	Rat, Mouse
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein amino acids 203-323 (Cytoplasmic Cterminus) of rat TARPGamma2
Formulation	PBS pH7.4, 50% glycerol
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	calcium voltage-gated channel auxiliary subunit gamma 2
Database Link	NP_445803 Entrez Gene 12300 MouseEntrez Gene 84347 Rat
Background	Stargazin belongs to a group called voltage gated calcium channels (VGCCs) which are present in most excitable cells. Stargazin is thought to stabilize the calcium channel in an inactivated (closed) state.There are five high voltage activated calcium channel types (L, N, P, Q, and R) and one low voltage activated channel type (T). Each of these channels exists as a heteromultimer of a1, b, a2/ d and g subunits with the voltage activated calcium channel function carried by the a subunits. VGCCs exert spatial and temporal control over cellular calcium concentrations and serve to modulate neurotransmitter release, hormone secretion, muscle contraction, electrical activity, cell metabolism and proliferation, gene expression, and neuronal survival.
Synonyms	MGC138502; MGC138504; stargazin
Note	Detects ~35-55kDa. Does not cross-react with TARPGamma3.
Reference Data

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