Bcan Mouse Monoclonal Antibody [Clone ID: S294A-6]

CAT#: TA326514

Mouse Monoclonal Anti-Brevican Antibody



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CNY 5,830.00


货期*
4周

规格
    • 100 ug

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Specifications

Product Data
Clone Name S294A-6
Recommend Dilution WB: 1:1000
Reactivity Rat, Mouse
Host Mouse
Clonality Monoclonal
Immunogen Fusion protein amino acids 219-655 of rat Brevican
Formulation PBS pH7.4, 50% glycerol
Concentration lot specific
Purification Protein G Purified
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Gene Name brevican
Background Brevican is the most abundant chondroitin sulfate proteoglycan in the extracellular matrix of the adultbrain. It is a member of the lectican family of aggregating extracellular matrix proteoglycans that bearchondroitin sulfate (CS) chains. It is highly expressed in the central nervous system and is thought to stabilize synapses and inhibit neural plasticity. Brevican is secreted from astrocytes and neurons as a 145 kD core protein that bears up to three, covalently-linked, CS chains. It is also is secreted as a 145 kD core protein without CS chains. When cleaved by extracellular glutamyl endopeptidases, the ADAMTSs, a 55 kD Nterminal fragment is formed that contains the unique Cterminal epitope EAMESE.
Synonyms BEHAB; brevican; CSPG7; MGC13038
Note Detects ~140kDa (and smaller due to proteolytic cleavage)
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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