AHA1 (AHSA1) Rat Monoclonal Antibody [Clone ID: 25F2.D9]

Specifications

Product Data
Clone Name	25F2.D9
Applications	IF, IP, WB
Reactivity	Human, Mouse, Rat
Host	Rat
Clonality	Monoclonal
Immunogen	Mouse Aha1
Formulation	0.02M potassium phosphate, 0.15M sodium chloride, pH7.2
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	activator of Hsp90 ATPase activity 1
Database Link	NP_036243 Entrez Gene 217737 MouseEntrez Gene 681996 RatEntrez Gene 10598 Human UniProt ID O95433
Background	Aha1 is a member of the Hsp90 cochaperone family, and is thought to stimulate Hsp90 ATPase activity by competing with p23 and other co-chaperones for Hsp90 binding . It may affect a step in the endoplasmic reticulum to Golgi trafficking. Aha1 also interacts with HSPCA/Hsp90 and with the cytoplasmic tail of the vesicular stomatistis virus glycoproteins (VSV G) . Aha1 is expressed in numerous tissues, including the brain, heart, skeletal muscle, and kidney, and at low levels, the liver and placenta. Aha1 might be a potential therapeutic strategy to increase sensitivity to HSP inhibitors .
Synonyms	AHA1; C14orf3; p38
Note	Detects ~38kDa. Can run up to 45kDa on SDS Page
Reference Data

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