Ankyrin G (ANK3) Mouse Monoclonal Antibody [Clone ID: S106-20]

Specifications

Product Data
Clone Name	S106-20
Applications	WB
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Fusion protein 1000 C-terminal amino acids of human Ankyrin G encompassing all of Ankyrin G with the exception of Ankyrin repeats
Formulation	PBS pH7.4, 50% glycerol, 0.09% sodium azide.
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	ankyrin 3, node of Ranvier (ankyrin G)
Database Link	NP_066267 Entrez Gene 11735 MouseEntrez Gene 361833 RatEntrez Gene 288 Human UniProt ID Q12955
Background	Ankyrins are a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin-actin based membrane skeleton . Ankyrins have binding sites for the beta subunit of spectrin and atleast 12 families of integral membrane proteins. This linkage is required to maintain the integrity of theplasma membranes and to anchor specific ion channels, ion exchangers and ion transporters in the plasma membrane.
Synonyms	ANKYRIN-G; MRT37
Note	Detects over 200kDa.
Reference Data
Protein Families	Druggable Genome

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