TXNDC5 Mouse Monoclonal Antibody [Clone ID: 2E7/7]

Specifications

Product Data
Clone Name	2E7/7
Recommend Dilution	WB: 1:200
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthesized peptide - 12 amino acids long (ADGEDGQDPHSK) corresponding to residues 52 - 63 of the EndoPDI protein
Formulation	PBS pH7.4, 50% glyercol and 0.09% sodium azide
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	thioredoxin domain containing 5
Database Link	NP_071368 Entrez Gene 81567 Human UniProt ID Q8NBS9
Background	Endothelial protein disulfide isomerase (EndoPDI) is a thioredoxin member of the protein disulfide isomerase family of chaperones. This enzyme has been localized to the endoplasmic reticulum in primary endothelial cells, but colocalizes with nucleoli in the nuclei of breast, colon, and renal cancer cells. EndoPDI mRNA and protein expression is induced by hypoxia and exhibits a protective effect on endothelial cells during hypoxia .
Synonyms	EndoPDI; ERP46; Hcc-2; MGC3178; thioredoxin domain containing 5; UNQ364
Note	Detects a protein with a mass of ~48kDa corresponding to EndoPDI
Reference Data
Protein Families	Druggable Genome

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