Sodium Iodide Symporter (SLC5A5) Mouse Monoclonal Antibody [Clone ID: 14F]

Specifications

Product Data
Clone Name	14F
Applications	WB
Recommend Dilution	WB: 1:1000
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Mannose binding protein hNIS fusion (AA468-643)
Formulation	PBS pH7.4, 50% glycerol, 0.09% sodium azide
Concentration	lot specific
Purification	Protein G Purified
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	solute carrier family 5 member 5
Database Link	NP_000444 Entrez Gene 114479 MouseEntrez Gene 114613 RatEntrez Gene 6528 Human UniProt ID Q92911
Background	The sodium iodide symporter (NIS) is an ion pump that actively transports iodide across the basolateral membrane into thyroid epithelial cells . This is important step in the process of iodide organificaton and the formation of triiodothyronine and thyroxine .
Synonyms	NIS; TDH1
Note	Apparent mol. wt of 97kD, non-glycosylated version at 68kD. Other minor bands associated with hNIS at160 kDa, and degradation products at ~30 kDa, and ~15kDa.
Reference Data
Protein Families	Druggable Genome, Transmembrane

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