Syntaxin 1a (STX1A) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000; IF/ICC: 1:100-1:500
Reactivity	Human, Mouse, Rat
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human Syntaxin 1A around the phosphorylation site of Serine 14
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	35 kDa
Gene Name	syntaxin 1A
Database Link	NP_001159375 Entrez Gene 20907 MouseEntrez Gene 116470 RatEntrez Gene 6804 Human UniProt ID Q16623
Background	STX1A is a type IV membrane protein involved in docking of synaptic vesicles at presynaptic active zones. May play a critical role in neurotransmitter exocytosis. Part of the SNARE core complex containing SNAP25, VAMP2 and STX1A. Three splice variant isoforms have been described.
Synonyms	HPC-1; P35-1; STX1; SYN1A
Reference Data
Protein Families	Druggable Genome, Secreted Protein, Transmembrane
Protein Pathways	SNARE interactions in vesicular transport

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