KAT2B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against a synthesized A synthesized peptide derived from human PCAF.
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	lysine acetyltransferase 2B
Database Link	NP_003875 Entrez Gene 18519 MouseEntrez Gene 301164 RatEntrez Gene 8850 Human UniProt ID Q92831
Background	PCAF Functions as a histone acetyltransferase (HAT) to promote transcriptional activation. Has significant histone acetyltransferase activity with core histones (H3 and H4), and also with nucleosome core particles. Inhibits cell-cycle progression and counteracts the mitogenic activity of the adenoviral oncoprotein E1A. In case of HIV-1 infection, it is recruited by the viral protein Tat
Synonyms	CAF; P; PCAF
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Notch signaling pathway

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