Insulin Receptor (INSR) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200
Reactivity	Human:Y1355
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human IR around the phosphorylation site of Tyrosine 1355
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	95 kDa
Gene Name	insulin receptor
Database Link	NP_000199 Entrez Gene 3643 Human UniProt ID P06213
Background	After removal of the precursor signal peptide, the insulin receptor precursor is post-translationally cleaved into two chains (alpha and beta) that are covalently linked. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake.
Synonyms	CD220; HHF5
Reference Data
Protein Families	Druggable Genome, Protein Kinase, Transmembrane
Protein Pathways	Adherens junction, Insulin signaling pathway, Type II diabetes mellitus

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