FOXO1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200
Reactivity	Human, Mouse, Rat
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human FOXO1/3/4-pan around the phosphorylation site of Threonine 24/32
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	78 kDa
Gene Name	forkhead box O1
Database Link	NP_002006 Entrez Gene 56458 MouseEntrez Gene 84482 RatEntrez Gene 2308 Human UniProt ID Q12778
Background	FOXO4 transcription factor AFX1 containing 1 fork-head domain. May play a role in the insulin signaling pathway. Involved in acute leukemias by a chromosomal translocation t(X;11)(q13;q23) that involves MLLT7 and MLL/HRX. The result is a rogue activator protein.
Synonyms	FKH1; FKHR; FOXO1A
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Insulin signaling pathway, Pathways in cancer, Prostate cancer

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