BLNK Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1:500-1:2000; IHC: 1:50-1:200
Reactivity	Human, Mouse
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	The antiserum was produced against A synthesized peptide derived from human BLNK around the phosphorylation site of Tyrosine 96
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific peptide.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	50 kDa
Gene Name	B-cell linker
Database Link	NP_001107566 Entrez Gene 17060 MouseEntrez Gene 29760 Human UniProt ID Q8WV28
Background	BLNK an adaptor protein that bridges the B-cell receptor-associated kinases (BCR) with a multitude of signaling pathways, regulating biologic outcomes of B-cell function and development. Plays an important role in BCR-mediated PLCG1 activation and Ca(2 ) mobilization.
Synonyms	AGM4; BASH; bca; BLNK-S; LY57; SLP-65; SLP65
Reference Data
Protein Families	Druggable Genome
Protein Pathways	B cell receptor signaling pathway, Primary immunodeficiency

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