Hsp75 (TRAP1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: K562, Jurkat, 293T cells IHC: 100-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a C terminal 300 amino acids of human TNF receptor-associated protein 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	80 kDa
Gene Name	TNF receptor associated protein 1
Database Link	NP_001258978 Entrez Gene 68015 MouseEntrez Gene 287069 RatEntrez Gene 10131 Human UniProt ID Q12931
Background	HSP90 proteins are highly conserved molecular chaperones that have key roles in signal transduction; protein folding; protein degradation; and morphologic evolution. HSP90 proteins normally associate with other cochaperones and play important roles in folding newly synthesized proteins or stabilizing and refolding denatured proteins after stress. TRAP1 is a mitochondrial HSP90 protein. Other HSP90 proteins are found in cytosol and endoplasmic reticulum
Synonyms	HSP 75; HSP75; HSP90L; TRAP-1
Reference Data
Protein Families	Druggable Genome

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