Calpain 2 (CAPN2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: Mouse brain and skin tissue, 293T cells
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 530-700 amino acids of Human Calpain-2 catalytic subunit
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	80 kDa
Gene Name	calpain 2
Database Link	NP_001139540 Entrez Gene 12334 MouseEntrez Gene 29154 RatEntrez Gene 824 Human UniProt ID P17655
Background	The calpains; calcium-activated neutral proteases; are nonlysosomal; intracellular cysteine proteases. The mammalian calpains include ubiquitous; stomach-specific; and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large; catalytic subunits associated with a common small; regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme; calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms	CANP2; CANPL2; CANPml; mCANP
Reference Data
Protein Families	Druggable Genome, Protease
Protein Pathways	Alzheimer's disease, Apoptosis, Focal adhesion

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