VMAT1 (SLC18A1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: A549 cells IHC: 10-50 Positive control: Human brain Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 104-117 amino acids of human solute carrier family 18 (vesicular monoamine), member 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56 kDa
Gene Name	solute carrier family 18 member A1
Database Link	NP_001135797 Entrez Gene 6570 Human UniProt ID P54219
Background	The vesicular monoamine transporter acts to accumulate cytosolic monoamines into vesicles; using the proton gradient maintained across the vesicular membrane. Its proper function is essential to the correct activity of the monoaminergic systems that have been implicated in several human neuropsychiatric disorders. The transporter is a site of action of important drugs; including reserpine and tetrabenazine.
Synonyms	CGAT; VAT1; VMAT1
Reference Data
Protein Families	Transmembrane
Protein Pathways	Parkinson's disease

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