Haptoglobin (HP) Rabbit Polyclonal Antibody
CAT#: TA323811
Anti-HP Rabbit Polyclonal Antibody
Size: 25 ul
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CNY 1,999.00
CNY 3,280.00
CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 200-1000 WB positive control: Human brain gliomas tissue IHC: 25-100 Positive control: Human lung cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein corresponding to a region derived from 162-406 amino acids of human haptoglobin |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 45 kDa |
Gene Name | haptoglobin |
Database Link | |
Background | This gene encodes a preproprotein; which is processed to yield both alpha and beta chains; which subsequently combine as a tetramer to produce haptoglobin. Haptoglobin functions to bind free plasma hemoglobin; which allows degradative enzymes to gain access to the hemoglobin; while at the same time preventing loss of iron through the kidneys and protecting the kidneys from damage by hemoglobin. Mutations in this gene and/or its regulatory regions cause ahaptoglobinemia or hypohaptoglobinemia. This gene has also been linked to diabetic nephropathy; the incidence of coronary artery disease in type 1 diabetes; Crohn's disease; inflammatory disease behavior; primary sclerosing cholangitis; susceptibility to idiopathic Parkinson's disease; and a reduced incidence of Plasmodium falciparum malaria. A similar duplicated gene is located next to this gene on chromosome 16. Multiple transcript variants encoding different isoforms have been found for this gene. |
Synonyms | BP; HP2ALPHA2; HPA1S |
Reference Data | |
Protein Families | Druggable Genome, Protease, Secreted Protein, Transmembrane |
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