Fibrillin 1 (FBN1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 2837-2853 amino acids of Human fibrillin 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	fibrillin 1
Database Link	NP_000129 Entrez Gene 14118 MouseEntrez Gene 2200 Human UniProt ID P35555
Background	This gene encodes a member of the fibrillin family. The encoded protein is a large; extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome; isolated ectopia lentis; autosomal dominant Weill-Marchesani syndrome; MASS syndrome; and Shprintzen-Goldberg craniosynostosis syndrome.
Synonyms	ACMICD; ECTOL1; FBN; GPHYSD2; MASS; MFS1; OCTD; SGS; SSKS; WMS; WMS2
Reference Data
Protein Families	Druggable Genome

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