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Polycystin 2 (PKD2) Rabbit Polyclonal Antibody
CAT＃: TA323703S
Anti-PKD2 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 25-100 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm, Nucleus |
| Reactivity | Human |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 956-968 amino acids of Human polycystic kidney disease 2 (autosomal dominant) |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | polycystin 2, transient receptor potential cation channel |
| Database Link | |
| Background | This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel; and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1; and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2. |
| Synonyms | APKD2; Pc-2; PC2; PKD4; TRPP2 |
| Reference Data | |
| Protein Families | Druggable Genome, Ion Channels: Transient receptor potential, Transmembrane |
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