Nociceptin receptor (OPRL1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 1000-5000 WB positive control: Human liver cancer tissue
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 360-380 amino acids of Human opiate receptor-like 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	41 kDa
Gene Name	opioid related nociceptin receptor 1
Database Link	NP_000904 Entrez Gene 18389 MouseEntrez Gene 29256 RatEntrez Gene 4987 Human UniProt ID P41146
Background	The protein encoded by this gene is a G protein-coupled receptor whose expression can be induced by phytohemagglutinin. The encoded integral membrane protein is a receptor for the 17 aa neuropeptide nociceptin/orphanin FQ. This gene may be involved in the regulation of numerous brain activities; particularly instinctive and emotional behaviors. A promoter for this gene also functions as a promoter for another gene; regulator of G-protein signalling 19 (RGS19); located on the opposite strand. Three transcript variants encoding the same protein have been found for this gene.
Synonyms	KOR-3; NOCIR; NOP; NOPr; OOR; ORL1
Reference Data
Protein Families	Druggable Genome, GPCR, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction

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