FOXB2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 10-50 Positive control: Human tonsil Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 411-424 amino acids of Human Forkhead box B2
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	forkhead box B2
Database Link	NP_001013757 Entrez Gene 442425 Human UniProt ID Q5VYV0
Background	FOX?(Forkhead box)?proteins?are a family of?transcription factors?that play important roles in regulating the expression of?genes?involved in cell growth; proliferation; differentiation; and?longevity. Many FOX proteins are important to embryonic development. The defining feature of FOX proteins is the forkhead box; a sequence of 80 to 100 amino acids forming a motif that binds to DNA. This forkhead motif is also known as the winged helix due to the butterfly-like appearance of the loops in the protein structure of the domain. Forkhead genes are a subgroup of the helix-turn-helix class of proteins. The FOXF2 gene encodes forkhead box F2; one of many human homologues of the Drosophila melanogaster transcription factor forkhead. FOXF2 is expressed in lung and placenta.
Synonyms	bA159H20.4
Reference Data

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