ENTR1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human prostate tissue IHC: 50-200 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 261-371 amino acids of human serologically defined colon cancer antigen 3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	46 kDa
Gene Name	serologically defined colon cancer antigen 3
Database Link	NP_001034796 Entrez Gene 68112 MouseEntrez Gene 10807 Human UniProt ID Q96C92
Background	SDCCAG3 protein contains the region similar to the coiled-coil domain of the myosin tail. The same domain is present in the proteins related to the organelles/proteins trafficking; such as kinesin; Golgin-160; and dynein. SDCCAG3 function might be related to protein trafficking and secretion; May be involved in modulation of TNF response; May be involved in presentation of TNFRSF1A on the cell surface. Interaction of SDCCAG3 with the Arf GTPase activating protein GIT1 (G protein-coupled receptor kinase interactor-1). Overexpression of an ArfGAP-negative version of GIT1 also results in an increased number of multinucleate cells suggesting regulation of Arf-mediated vesicular trafficking or signaling via SDCCAG3.
Synonyms	NY-CO-3
Reference Data

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