AGRP Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 50-63 amino acids of human agouti related protein homolog (mouse)
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	agouti related neuropeptide
Database Link	NP_001129 Entrez Gene 181 Human UniProt ID O00253
Background	This gene encodes an antagonist of the melanocortin-3 and melanocortin-4 receptor. It appears to regulate hypothalamic control of feeding behavior via melanocortin receptor and/or intracellular calcium regulation; and thus plays a role in weight homeostasis. Mutations in this gene have been associated with late on-set obesity.
Synonyms	AGRT; ART; ASIP2
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Adipocytokine signaling pathway

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