ARF1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Human fetal brain and kidney tissue IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 100-115 amino acids of Human ADP-ribosylation factor 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	21 kDa
Gene Name	ADP ribosylation factor 1
Database Link	NP_001649 Entrez Gene 11840 MouseEntrez Gene 64310 RatEntrez Gene 375 Human UniProt ID P84077
Background	ADP-ribosylation factor 1 (ARF1) is a member of the human ARF gene family. The family members encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking as activators of phospholipase D. The gene products; including 6 ARF proteins and 11 ARF-like proteins; constitute a family of the RAS superfamily. The ARF proteins are categorized as class I (ARF1; ARF2 and ARF3); class II (ARF4 and ARF5) and class III (ARF6); and members of each class share a common gene organization. The ARF1 protein is localized to the Golgi apparatus and has a central role in intra-Golgi transport. Multiple alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms	ADP-ribosylation factor 1; OTTHUMP00000035715
Reference Data
Protein Pathways	Vibrio cholerae infection

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