FOXO1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Hela cell lysate IHC: 25-100 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse, Rat
Modifications	Phospho-specific
Host	Rabbit
Clonality	Polyclonal
Immunogen	Peptide sequence around phosphorylation site of serine 256 (A-A-S(p)-M-D) derived from Human FKHR.
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	70 kDa
Gene Name	forkhead box O1
Database Link	NP_002006 Entrez Gene 56458 MouseEntrez Gene 84482 RatEntrez Gene 2308 Human UniProt ID Q12778
Background	This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma.
Synonyms	FKH1; FKHR; FOXO1A
Reference Data
Protein Families	Druggable Genome, Transcription Factors
Protein Pathways	Insulin signaling pathway, Pathways in cancer, Prostate cancer

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