Histidine decarboxylase (HDC) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 5-20 Positive control: Human colon cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a C terminal 300 amino acids of human histidine decarboxylase
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	histidine decarboxylase
Database Link	NP_002103 Entrez Gene 15186 MouseEntrez Gene 3067 Human UniProt ID P19113
Background	This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes; including neurotransmission; gastric acid secretion;inflamation; and smooth muscle tone.
Synonyms	MGC163399
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Histidine metabolism, Metabolic pathways

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