GPBB (PYGB) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: HT-29 cells
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 1-15 amino acids of Human phosphorylase, glycogen; brain
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	97 kDa
Gene Name	phosphorylase, glycogen; brain
Database Link	NP_002853 Entrez Gene 25739 RatEntrez Gene 110078 MouseEntrez Gene 5834 Human UniProt ID P11216
Background	The protein encoded by this gene is a glycogen phosphorylase found predominantly in the brain. The encoded protein forms homodimers which can associate into homotetramers; the enzymatically active form of glycogen phosphorylase. The activity of this enzyme is positively regulated by AMP and negatively regulated by ATP; ADP; and glucose-6-phosphate. This enzyme catalyzes the rate-determining step in glycogen degradation
Synonyms	GPBB
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Insulin signaling pathway, Starch and sucrose metabolism

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