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GDNF Receptor alpha 1 (GFRA1) Rabbit Polyclonal Antibody
CAT＃: TA322638S
Anti-GFRA1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: Rat brain tissue lysate IHC: 50-200 Positive control: Human brain Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 370-384 amino acids of Human GDNF family receptor alpha 1 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 51 kDa |
| Gene Name | GDNF family receptor alpha 1 |
| Database Link | |
| Background | Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related; potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN; and mediates activation of the RET tyrosine kinase receptor. This gene is a candidate gene for Hirschsprung disease. Multiple alternatively spliced transcript variants have been described for this gene. |
| Synonyms | GDNFR; GDNFRA; GFR-ALPHA-1; RET1L; RETL1; TRNR1 |
| Reference Data | |
| Protein Families | Druggable Genome |
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