IMP3 (IGF2BP3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: A172, hela and hepg2 cells
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to a region derived from 382-579 amino acids of human insulin-like growth factor 2 mRNA binding protein 3
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	64 kDa
Gene Name	insulin like growth factor 2 mRNA binding protein 3
Database Link	NP_006538 Entrez Gene 140488 MouseEntrez Gene 10643 Human UniProt ID O00425
Background	The protein encoded by this gene is primarily found in the nucleolus; where it can bind to the 5' UTR of the insulin-like growth factor II leader 3 mRNA and may repress translation of insulin-like growth factor II during late development. The encoded protein contains several KH domains; which are important in RNA binding and are known to be involved in RNA synthesis and metabolism. A pseudogene exists on chromosome 7; and there are putative pseudogenes on other chromosomes.?
Synonyms	CT98; IMP-3; IMP3; KOC; KOC1; VICKZ3
Reference Data

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