CD93 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm and Cell membrane
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 539-542 amino acids of human CD93 molecule
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	CD93 molecule
Database Link	NP_036204 Entrez Gene 17064 MouseEntrez Gene 84398 RatEntrez Gene 22918 Human UniProt ID Q9NPY3
Background	The protein encoded by this gene is a cell-surface glycoprotein and type I membrane protein that was originally identified as a myeloid cell-specific marker. The encoded protein was once thought to be a receptor for C1q; but now is thought to instead be involved in intercellular adhesion and in the clearance of apoptotic cells. The intracellular cytoplasmic tail of this protein has been found to interact with moesin; a protein known to play a role in linking transmembrane proteins to the cytoskeleton and in the remodelling of the cytoskeleton.
Synonyms	C1qR(P); C1QR1; C1qRP; CDw93; dJ737E23.1; ECSM3; MXRA4
Reference Data
Protein Families	Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

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