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Calpain 6 (CAPN6) Rabbit Polyclonal Antibody
CAT＃: TA322386S
Anti-CAPN6 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 500-2000 WB positive control: TM4 and NIH/3T3 cell lysates IHC: 50-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 26-343 amino acids of human calpain 6 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | calpain 6 |
| Database Link | |
| Background | Calpains are ubiquitous; well-conserved family of calcium-dependent; cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large subunit possesses a cysteine protease domain; and both subunits possess calcium-binding domains. Calpains have been implicated in neurodegenerative processes; as their activation can be triggered by calcium influx and oxidative stress. The protein encoded by this gene is highly expressed in the placenta. Its C-terminal region lacks any homology to the calmodulin-like domain of other calpains. The protein lacks critical active site residues and thus is suggested to be proteolytically inactive. The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis. |
| Synonyms | CalpM; CANPX; CAPNX; DJ914P14.1 |
| Reference Data | |
| Protein Families | Druggable Genome, Protease |
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