SEMA3G Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human colorectal cancer Predicted cell location: Secreted
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 250 amino acids of human sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	semaphorin 3G
Database Link	NP_064548 Entrez Gene 56920 Human UniProt ID Q9NS98
Background	Semaphorins?are a class of secreted and membrane?proteins?that act as?axonal?growth cone?guidance molecules. They primarily act as short-range inhibitory signals and signal through multimeric?receptor?complexes. They are usually cues to deflect axons from inappropriate regions; especially important in?neural system?development. The major class of proteins that act as their receptors are called?plexins.SEMA3G possesses anti-migration and anti-invasion ability. SEMA3G inhibited tumor cell migration and invasion; which may be obtained through cell autonomous or paracrine mechanisms; and SEMA3G is a potential target for antitumor migration and invasion.
Synonyms	sem2
Reference Data
Protein Families	Druggable Genome, Secreted Protein
Protein Pathways	Axon guidance

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