Secretin (SCT) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 34-49 amino acids of human secretin
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	secretin
Database Link	NP_068739 Entrez Gene 20287 MouseEntrez Gene 24769 RatEntrez Gene 6343 Human UniProt ID P09683
Background	Secretin belongs to the glucagon family. This protein is an endocrine hormone and its major site of production is the endocrine S cells located in the proximal small intestinal mucosa. The release of active secretin is stimulated by either fatty acids or an acidic pH in the duodenum. This hormone stimulates the secretion of bicarbonate-rich pancreatic fluids and has also been shown to regulate the growth and development of the stomach; small intestine; and pancreas. Secretin deficiency has been implicated in autistic syndrome; suggesting that the hormone could have a neuroendocrine function in addition to its role in digestion.
Synonyms	secretin
Reference Data
Protein Families	Druggable Genome, Secreted Protein

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