Cyclin B1 (CCNB1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: Jurkat, 231 and Hela cells
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 61-74 amino acids of Human cyclin B1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	48 kDa
Gene Name	cyclin B1
Database Link	NP_114172 Entrez Gene 891 Human UniProt ID P14635
Background	G2/mitotic-specific cyclin-B1 is a protein that in humans is encoded by the CCNB1 gene. The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found; a constitutively expressed transcript and a cell cycle-regulated transcript; that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites.
Synonyms	CCNB
Reference Data
Protein Families	Druggable Genome, Stem cell - Pluripotency
Protein Pathways	Cell cycle, Oocyte meiosis, p53 signaling pathway, Progesterone-mediated oocyte maturation

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