Caspase 10 (CASP10) Rabbit Polyclonal Antibody

CAT#: TA322125S

Anti-CASP10 Rabbit Polyclonal Antibody

Size: 25 ul 100 ul



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CNY 800.00

CNY 1,280.00


货期*
2周

规格
    • 25 ul

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: Human liver cancer tissue
IHC: 25-100
Positive control: Human brain
Predicted cell location: Cytoplasm
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen Synthetic peptide corresponding to a region derived from 485-499 amino acids of Human caspase 10, apoptosis-related cysteine peptidase
Formulation PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C as received.
Predicted Protein Size 54 kDa
Gene Name caspase 10
Background This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits; large and small; that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7; and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome; non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Synonyms ALPS2; FLICE2; MCH4
Reference Data
Protein Families Druggable Genome, Protease
Protein Pathways Apoptosis, RIG-I-like receptor signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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