SP1 Rabbit Polyclonal Antibody
CNY 1,999.00
CNY 3,280.00
货期*
2周
规格
Cited in 1 publication. |
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Nucleus |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide corresponding to a region derived from 609-622 amino acids of human Sp1 transcription factor |
Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Gene Name | Sp1 transcription factor |
Database Link | |
Background | The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes; including cell differentiation; cell growth; apoptosis; immune responses; response to DNA damage; and chromatin remodeling. Post-translational modifications such as phosphorylation; acetylation; glycosylation; and proteolytic processing significantly affect the activity of this protein; which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. |
Synonyms | Sp1 transcription factor; specificity protein 1 |
Reference Data | |
Protein Families | Druggable Genome, ES Cell Differentiation/IPS, Stem cell - Pluripotency, Stem cell relevant signaling - JAK/STAT signaling pathway, Transcription Factors |
Protein Pathways | Huntington's disease, TGF-beta signaling pathway |
Citations (1)
The use of this Antibodies has been cited in the following citations: |
---|
CG223, a novel BET inhibitor, exerts TGF-β1-mediated antifibrotic effects in a murine model of bleomycin-induced pulmonary fibrosis
,null,
Pulmonary Pharmacology Therapeutics
,PubMed ID 34425215
[SP1]
|
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