SLC22A6 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Human fetal kidney tissue IHC: 50-200 Positive control: Human breast cancer Predicted cell location: Cytoplasm
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 551-563 amino acids of Human solute carrier family 22 (organic anion transporter), member 6
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	56 kDa
Gene Name	solute carrier family 22 member 6
Database Link	NP_695009 Entrez Gene 29509 RatEntrez Gene 9356 Human UniProt ID Q4U2R8
Background	The protein encoded by this gene is involved in the sodium-dependent transport and excretion of organic anions; some of which are potentially toxic. The encoded protein is an integral membrane protein and may be localized to the basolateral membrane. Four transcript variants encoding four different isoforms have been found for this gene. Functions as organic anion exchanger when the uptake of one molecule of organic anion is coupled with an efflux of one molecule of endogenous dicarboxylic acid (glutarate; ketoglutarate; etc). Mediates the sodium-independent uptake of 2;3-dimercapto-1-propanesulfonic acid (DMPS) By similarity.
Synonyms	HOAT1; OAT1; PAHT; ROAT1
Reference Data
Protein Families	Transmembrane

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