E2F7 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 50-200 Positive control: Human colon cancer Predicted cell location: Cytoplasm, Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide corresponding to a region derived from 53-66 amino acids of human E2F transcription factor 7
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Gene Name	E2F transcription factor 7
Database Link	NP_976328 Entrez Gene 144455 Human UniProt ID Q96AV8
Background	Atypical E2F transcription factor that participates to various processes such as angiogenesis; polyploidization of specialized cells and DNA damage response. It plays a key role in polyploidization of cells in placenta and liver by regulating the endocycle; probably by repressing genes promoting cytokinesis and antagonizing action of classical E2F proteins (E2F1; E2F2 and/or E2F3).
Synonyms	FLJ12981
Reference Data
Protein Families	Transcription Factors

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