SPATA16 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse brain tissue lysate IHC: 150-300 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 250 amino acids of human spermatogenesis associated 16
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	65 kDa
Gene Name	spermatogenesis associated 16
Database Link	NP_114161 Entrez Gene 70862 MouseEntrez Gene 83893 Human UniProt ID Q9BXB7
Background	This gene encodes a testis-specific protein that belongs to the tetratricopeptide repeat-like superfamily. The encoded protein localizes to the Golgi apparatus and may play a role in spermatogenesis. The SPATA16 protein contains a region of homology to the mouse male enhanced antigen-2; a SCOP domain belonging to the tetratricopeptide repeat-like superfamily; 3 glycosylation sites; and several phosphorylation sites. The mouse and human proteins share 77% sequence identity. Northern blot analysis of multiple human tissues detected a strong signal in testis and weak expression in pancreas and kidney. Laser confocal microscopy localized a GFP-SPATA16 fusion protein specifically to the Golgi apparatus.
Synonyms	NYD-SP12; SPGF6
Reference Data

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