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RASSF1 Rabbit Polyclonal Antibody
CAT＃: TA321802S
Anti-RASSF1 Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC, WB |
| Recommend Dilution | WB: 200-1000 WB positive control: 293T cell lysate IHC: 25-50 Positive control: Human tonsil Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 120-133 amino acids of human Ras association (RalGDS/AF-6) domain family member 1 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Predicted Protein Size | 39 kDa |
| Gene Name | Ras association domain family member 1 |
| Database Link | |
| Background | This gene encodes a protein similar to the RAS effector proteins. Loss or altered expression of this gene has been associated with the pathogenesis of a variety of cancers; which suggests the tumor suppressor function of this gene. The inactivation of this gene was found to be correlated with the hypermethylation of its CpG-island promoter region. The encoded protein was found to interact with DNA repair protein XPA. The protein was also shown to inhibit the accumulation of cyclin D1; and thus induce cell cycle arrest. Several alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. |
| Synonyms | 123F2; NORE2A; RASSF1A; RDA32; REH3P21 |
| Reference Data | |
| Protein Families | Druggable Genome |
| Protein Pathways | Bladder cancer, Non-small cell lung cancer, Pathways in cancer |
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Rabbit anti-RASSF1 Polyclonal Antibody
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