Hsp105 (HSPH1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 500-2000 WB positive control: PC3 cells, human colon cancer and liver cancer tissue
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein corresponding to C terminal 300 amino acids of human heat shock 105kDa/110kDa protein 1
Formulation	PBS pH7.3, 0.05% NaN3, 50% glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	97 kDa
Gene Name	heat shock protein family H (Hsp110) member 1
Database Link	NP_006635 Entrez Gene 15505 MouseEntrez Gene 288444 RatEntrez Gene 10808 Human UniProt ID Q92598
Background	Heat shock protein 105 kDa?is a?protein?that in humans is encoded by the?HSPH1?gene. Prevents the aggregation of denatured proteins in cells under severe stress; on which the ATP levels decrease markedly. Inhibits HSPA8/HSC70 ATPase and chaperone activities. Highly expressed in testis. Present at lower levels in most brain regions; except cerebellum. Overexpressed in cancer cells. Phosphorylation on Ser-509 may be important for regulation of the HSPA8/HSC70 chaperone activity.
Synonyms	HSP105; HSP105A; HSP105B; NY-CO-25
Reference Data
Protein Families	Stem cell - Pluripotency

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