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PTP epsilon (PTPRE) Rabbit Polyclonal Antibody
CAT＃: TA321767S
Anti-PTPRE Rabbit Polyclonal Antibody
Size: 100 ul
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CNY 800.00
CNY 1,280.00
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CNY 300.00
CNY 1,430.00
CNY 2,900.00
CNY 6,650.00
CNY 3,080.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 15-50 Positive control: Human ovarian cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Fusion protein corresponding to a region derived from 426-689 amino acids of human protein tyrosine phosphatase, receptor type, E |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | protein tyrosine phosphatase, receptor type E |
| Database Link | |
| Background | The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth; differentiation; mitotic cycle; and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported; one of which encodes a receptor-type PTP that possesses a short extracellular domain; a single transmembrane region; and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus; and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways; cytokines induced SATA signaling; as well as the activation of voltage-gated K+ channels. |
| Synonyms | HPTPE; PTPE; R-PTP-EPSILON |
| Reference Data | |
| Protein Families | Druggable Genome, Phosphatase, Transmembrane |
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