United States
Germany
Japan
United Kingdom
China
Fibulin 5 (FBLN5) Rabbit Polyclonal Antibody
CAT＃: TA321761S
Anti-FBLN5 Rabbit Polyclonal Antibody
Size: 100 ul
Need it in bulk or conjugated?
Get a free quote
CNY 800.00
CNY 1,280.00
Product images
CNY 300.00
CNY 1,430.00
Specifications
| Product Data | |
| Applications | IHC |
| Recommend Dilution | IHC: 50-200 Positive control: Human lung cancer Predicted cell location: Cytoplasm |
| Reactivity | Human, Mouse, Rat |
| Host | Rabbit |
| Clonality | Polyclonal |
| Immunogen | Synthetic peptide corresponding to a region derived from 408-422 amino acids of Human fibulin 5 |
| Formulation | PBS pH7.3, 0.05% NaN3, 50% glycerol |
| Purification | Antigen affinity purification |
| Conjugation | Unconjugated |
| Storage Condition | Store at -20°C as received. |
| Gene Name | fibulin 5 |
| Database Link | |
| Background | The protein encoded by this gene is a secreted; extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However; its expression is reinduced in balloon-injured vessels and atherosclerotic lesions; notably in intimal vascular smooth muscle cells and endothelial cells. Therefore; the protein encoded by this gene may play a role in vascular development and remodeling. Defects in this gene are a cause of autosomal dominant cutis laxa; autosomal recessive cutis laxa type I (CL type I); and age-related macular degeneration type 3 (ARMD3). |
| Synonyms | ADCL2; ARCL1A; ARMD3; DANCE; EVEC; FIBL-5; HNARMD; UP50 |
| Reference Data | |
| Protein Families | Secreted Protein |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
| 抗体相关资料 |
其它Fibulin 5产品
